邮箱：penggy@bucm.edu.cn 010-53912169
个人简介
彭桂英，教授，博士生导师，现任2278游戏中心官网免疫与微生物教研室主任,兼任世界中医药学会联合会过敏性疾病专业委员会常务理事、中国民族医药学会大数据人工智能分会常务理事、中华中医药学会免疫分会常委、中华中医药学会体质分会委员、中国免疫学会中医药免疫学分会委员以及中国病理生理学会炎症发热感染低温专业委员会委员。主持国家自然科学基金项目4项,参与国家重点研发计划项目1项，参与多项国家级和省部级课题。在Gut microbes、Biomedicine&Pharmacotherapy、Food&Function、Journal of leukocyte biology、Nature immunology等专业杂志发表论文80余篇，授权专利4项。参编国家级教材5部，荣获2023年2278游戏中心官网青年教学名师，指导学生荣获第十八届“挑战杯”全国大学生课外学术科技作品竞赛国奖三等奖。
研究方向
中医药干预呼吸系统和消化系统疾病的机制研究。
主要成果
1. Li Q#, Zhang C#, Xu G, Shang X, Nan X, Li Y, Liu J, Hong Y, Wang Q*, Peng G*. Astragalus polysaccharide ameliorates CD8+T cell dysfunction through STAT3/Gal-3/LAG3 pathway in inflammation‐induced colorectal cancer. Biomed Pharmacother,2024; 171:116172.
2. Na Li#, Peiguang Ma#, Yalan Li#, Xuekai Shang, Xinmei Nan, Lei Shi, Xiao Han, Jiajing Liu, Yanfei Hong, Qiuyi Li, Jiaqi Cui, Junxiang Li* and Guiying Peng*. Gut microbiota-derived 12-ketolithocholic acid suppresses the IL-17A secretion from colonic group 3 innate lymphoid cells to prevent the acute exacerbation of ulcerative colitis. Gut Microbes. 2023;15(2):2290315.
3. Zirui Liu#, Yalan Li#, Na Li, Yongan Wang, Qiuyi Li, Dongyu Ge, Guiying Peng*, Mengyu Zhou*, Dachengqi Decoction alleviates intestinal inflammation in ovalbumin-induced asthma by reducing group 2 innate lymphoid cells in a microbiota-dependent manner, Journal of Traditional and Complementary Medicine,2023; 13(2):183-192
4. Nan X#, Zhao W, Liu WH, Li Y, Li N, Hong Y, Cui J, Shang X, Feng H, Hung WL*, Peng G*. Bifidobacterium animalis subsp. lactis BL-99 ameliorates colitis-related lung injury in mice by modulating short-chain fatty acid production and inflammatory monocytes/macrophages. Food Funct. 2023;14(2):1099-1112.
5. Yanfei Hong#, Zhulang Chu#, Jingwei Kong, Qiuyi Li, Na Li, Liting Liu,TongWu, Jiajing Liu, Dongyu Ge, Jie Li*, Gui-ying Peng*. IL-17A aggravates asthma-induced intestinal immune injury by promoting neutrophil trafficking. Journal of leukocyte biology.2022;112(3):425-435
6. Hong-shuang Liu#, Man-yu Zhou#, Xi Zhang, Ya-lan Li, Jing-wei Kong, Xin Gao, Dong-yu Ge, Jia-jing Liu, Pei-guang Ma, Gui-ying Peng*, Yan Liao*.Sagittaria sagittifolia polysaccharide protects against six-heavy-metal-induced hepatic injury associated with the activation of Nrf2 pathway to regulate oxidative stress and apoptosis. Journal of Inorganic Biochemistry. 2022;111810.
7. Li Y#, Li N#, Liu J, Wang T, Dong R, Ge D, Peng G*. Gegen Qinlian Decoction Alleviates Experimental Colitis and Concurrent Lung Inflammation by Inhibiting the Recruitment of Inflammatory Myeloid Cells and Restoring Microbial Balance. J Inflamm Res. 2022;15:1273-1291.
8. Wang Y#, Li N#, Li Q, Liu Z, Li Y, Kong J, Dong R, Ge D, Li J, Peng G*. Xuanbai Chengqi Decoction Ameliorates Pulmonary Inflammation via Reshaping Gut Microbiota and Rectifying Th17/Treg Imbalance in a Murine Model of Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis. 2021 Dec 7;16:3317-3335.
9. Ding P, Liu J, Li Q, Lu Q, Li J, Shi R, Shi L, Mao T, Ge D, Niu H, Peng G*, Wang Z. Investigation of the Active Ingredients and Mechanism of Hudi Enteric-Coated Capsules in DSS-Induced Ulcerative Colitis Mice Based on Network Pharmacology and Experimental Verification. Drug Des Devel Ther. 2021;15:4259-4273.
10. Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu YC*. The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells. Nat Immunol. 2014,15(7):657-666.