研究生教育

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王如峰

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邮箱:wangrufeng@tsinghua.org.cn

个人简介

生药学博士、2278游戏中心官网教授、博士生导师。先后主持和承担国家自然科学基金、重大新药创制科技重大专项、国家重点研发计划、教育部留学回国基金、北京市自然科学基金、企业横向课题等项目10余项。发表学术论文100余篇,获得授权发明专利9项。

研究方向

1)中药化学成分及其生物活性;

2)中药化学成分体内代谢;

3)中药化学成分-肠道微生物相互作用。

主要成果

[1] Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C-glycoside cleaving enzyme and an O- to C-glycoside isomerase. Acta Pharmaceutica Sinica B, 2023, 13(1): 246-255.

[2] Screening quality makers (Q-makers) of Xiaoer Chaige Tuire Oral Liquid by in vitro sequential metabolism and in vivo biopharmaceutical analysis. Phytomedicine, 2023, 116: 154844.

[3] Synergistic antibacterial effect and mechanism of allicin and an Enterobacter cloacae bacteriophage. Microbiology Spectrum, 2023, 11(1): e0315522.

[4] Interaction between Changan Granule and its main components in the plasma and CYP450 enzymes. Journal of Ethnopharmacology, 2023, 308: 116303.

[5] Mechanism of berberine hydrochloride interfering with biofilm formation of Hafnia alvei. Archives of Microbiology, 2022, 204: 126.