研究生教育

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刘颖

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邮箱:liuyliwd@vip.sina.com

个人简介

2004/08-2016/10  2278游戏中心官网中药学院助教、讲师、副研究员

2016/11-至今        2278游戏中心官网副研究员、研究员

2018/03-2019/03  美国匹兹堡大学医学院,访问学者

研究方向

1)药用植物功能基因与合成生物学研究

2)中药“分子身份证”研究

3)中药抗糖尿病活性成分的筛选及分子机制研究

主要成果

以第一作者及通讯作者发表SCI论文20余篇,核心期刊论文50余篇。代表作如下:

[1] Licochalcone A alleviates abnormal glucolipid metabolism and restores energy homeostasis in diet-induced diabetic mice, Phytotherapy Research, 2024, 38(1): 196-213. DOI: 10.1002/ptr.8044

[2] The role of autophagy in insulin resistance and glucolipid metabolism and potential use of autophagy modulating natural products in the treatment of type 2 diabetes mellitus, Diabetes/Metabolism Research and Reviews, 2024, 40(1): e3762. DOI: 10.1002/dmrr.3762

[3] The potential of therapeutic strategies targeting mitochondrial biogenesis for the treatment of insulin resistance and type 2 diabetes mellitus, Archives of Pharmacal Research, 2024, 47(3): 219-248. DOI: 10.1007/s12272-024-01490-5

[4] Isoliquiritigenin, a potential therapeutic agent for treatment of inflammation-associated diseases, Journal of Ethnopharmacology, 2024, 318(Pt B): 117059. DOI: 10.1016/j.jep.2023.117059

[5] COMT, CRTZ, and F3'H regulate glycyrrhizic acid biosynthesis in Glycyrrhiza uralensis hairy roots, Plant Growth Regulation, 2023, 101(1): 115-130. DOI: 10.1007/s10725-023-01005-0

[6] Isoliquiritigenin alleviates diabetic symptoms via activating AMPK and inhibiting mTORC1 signaling in diet-induced diabetic mice, Phytomedicine, 2022, 98: 153950. DOI: 10.1016/j.phymed.2022.153950

[7] ARPI, β-AS, and UGE regulate glycyrrhizin biosynthesis in Glycyrrhiza uralensis hairy roots, Plant Cell Reports, 2021, 40 (7): 1285-1296. DOI: 10.1007/s00299-021-02712-6

[8] Molecular mechanisms underlying the anticancer activities of licorice flavonoids, Journal of Ethnopharmacology, 2021, 267: 113635. DOI: 10.1016/j.jep.2020.113635

[9] The anti-diabetic activity of licorice, a widely used Chinese herb, Journal of Ethnopharmacology, 2020, 263: 113216. DOI: 10.1016/j.jep.2020.113216

[10] Identification of biosynthetic pathways involved in flavonoid production in licorice by RNA-seq based transcriptome analysis, Plant growth regulation, 2020, 92 (1): 15-28. DOI: 10.1007/s10725-020-00616-1

主持国家自然科学基金1项、北京市青年英才计划1项、国家工业和信息化部中药材扶持项目1项、2278游戏中心官网杰出青年人才项目1项、中央高校基本科研项目1项。

指导大学生创新课题1项,研究生课题2项。共指导研究生11届,21人,其中4人获得国家奖学金,19人获得学业一等奖学金,已毕业8届,16人。