研究生教育

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赵丕文

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邮箱:pwzhao@263.net

个人简介

1、 2000/01至2016/08,2278游戏中心官网,基础医学院

2、 2016/09至今,2278游戏中心官网,2278游戏中心官网

研究方向

妇科常用中药的配伍规律及其分子药理机制的研究

主要成果

科研团队近年来一直从事中医药防治妇科疾病相关领域的理论和临床基础研究,曾获得北京市科技进步三等奖、中国中西医结合学会科技进步二等奖等科研奖励。

近年来发表研究论文130余篇,SCI论文20余篇;编写科研专著3部。

代表作如下:


[1] Liu J, Yang Y, He Y, Feng C, Ou H, Yang J, Chen Y, You F, Shao B, Bao J, Guan X, Chen F, Zhao P. Erxian decoction alleviates cisplatin-induced premature ovarian failure in rats by reducing oxidation levels in ovarian granulosa cells. J Ethnopharmacol. 2023,304:116046.

[2] Liu J, Shi D, Ma Q, Zhao P. Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H2O2-induced human granulosa cell line KGN. J Ethnopharmacol. 2022,295:115398.

[3] Shi D, Li H, Zhang Z, He Y, Chen M, Sun L, Zhao P*. Cryptotanshinone inhibits proliferation and induces apoptosis of breast cancer MCF-7 cells via GPER mediated PI3K/AKT signaling pathway [J]. PLoS One, 2022,17(1):e0262389

[4] Zhang Z, Liu J, Liu Y, Shi D, He Y, Zhao P*. Virtual screening of the multi-gene regulatory molecular mechanism of Si-Wu-tang against non-triple-negative breast cancer based on network pharmacology combined with experimental validation [J]. J Ethnopharmacol, 2020,269:113696.

[5] Shi D, Zhao P*, Cui L, Li H, Sun L, Niu J, Chen M. Inhibition of PI3K/AKT molecular pathway mediated by membrane estrogen receptor GPER accounts for cryptotanshinone induced antiproliferative effect on breast cancer SKBR-3 cells [J]. BMC Pharmacol Toxicol. 2020,21(1):32-41.